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February 22, 1980

The Neurobiologic Mechanisms in Manipulative Therapy

Author Affiliations

Rehabilitation Institute of Chicago Northwestern University-McGaw Medical Center Chicago College of Osteopathic Medicine

JAMA. 1980;243(8):805. doi:10.1001/jama.1980.03300340063032

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This is a stimulating book presenting insights into the goals and uses of manipulative therapy. It documents the opinions of practitioners of many disciplines who ordinarily do not meet. Both clinical experiences and scientific methodologies are discussed. Questions are raised that should stimulate new and different approaches.

One is impressed with the amount of research and thinking that has gone into explaining the effectiveness of manipulative therapy. Nevertheless, further work is needed both in research and integration of the findings. More documentation especially is needed from the practitioner. There appears to be a genuine need for standardization of terminology between different disciplines. Much should also be done with controlled studies either with human or animal models.

This enlightening book is well worth reading. To date, most of what has been written has consisted of individual concepts, experiences, and anecdotes.