by Jerome Lowenstein, 154 pp, with illus, $35, ISBN 0-19-507572-2, paper $14.95, ISBN 0-19-507573-0, New York, NY, Oxford University Press, 1993.
Among the many intellectual challenges encountered by medical students, residents, and practitioners, that of interpreting clinical acid-base disorders remains one of the most difficult challenges to master. This short book is an attempt "to lead the uninitiated and the timid to an understanding of acid-base disorders."
The author was encouraged to write yet another book on the subject of acid-base disorders because of "explosion in knowledge regarding the molecular basis for membrane transport" in the last decade. To acquaint the beginning reader with the basic molecular mechanisms, the author provides an excellent, albeit brief, description of the importance of pH in life and the role played by various primary and secondary active transport pathways involved in regulation of intracellular pH. The discussion of transport pathways involved in proton secretion is laudable and unusual for a short primer and accounts for the strength of the book. I gave a copy to
Kaji DM. Acid and Basics: A Guide to Understanding Acid-Base Disorders. JAMA. 1994;271(13):1041. doi:10.1001/jama.1994.03510370095041