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April 25, 1980

Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) in Adults-Reply

Author Affiliations

University of Missouri Medical Center Columbia

JAMA. 1980;243(16):1631. doi:10.1001/jama.1980.03300420015013

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In Reply.—  As indicated in the article, "Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) in Adults," the diagnosis at present depends on a collection of symptoms and signs that fit a syndrome. The patients described did not have localized staphylococcal disease, but neither nasopharyngeal cultures nor vaginal cultures were performed specifically to look for staphylococci or toxin production by such organisms. The purpose of the report was to call attention to a compatible syndrome occurring in adults. In such a limited number of cases, it could be serendipitous that all were women, and, certainly, Kawasaki disease can be of varying severity. Since these patients were not investigated for toxin, they may have had toxic shock syndrome; nevertheless they fit the criteria for mucocutaneous lymph node syndrome. In the event that a serological test becomes available, I have frozen sera from two of the three cases for further study.