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April 13, 1994

Hans Krebs: Architect of Intermediary Metabolism 1933-1937

Author Affiliations

University of Miami (Fla)

JAMA. 1994;271(14):1137-1138. doi:10.1001/jama.1994.03510380095054

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This is the second and concluding volume of Holmes' biography of Hans Krebs. Holmes has chosen not to recount the next 44 years of Krebs' life, as the year 1937 marks the beginning of another phase. At that time Krebs stopped working at the bench and carried out his research through a group of technicians, graduate students, and fellows, assembled under his leadership.

This volume begins with Krebs' arrival in England in 1933 as a refugee from Nazi Germany and his going to work in Hopkins' laboratory in Cambridge, where he continued to pursue the themes he developed in Germany using techniques learned in Warburg's laboratory.

The author shares in detail almost every day of Krebs' laboratory notebook entries on his experiments, annotated by Holmes' own interpretations and an occasional comment by Krebs from interviews conducted in 1977. Notable life events described are Krebs' move from Cambridge to Sheffield; protracted,

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