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January 15, 1988

You Don't Have to Be a Neuroscientist to Forget Everything With Triazolam—But It Helps

Author Affiliations

Oceanside, NY

Oceanside, NY

JAMA. 1988;259(3):351. doi:10.1001/jama.1988.03720030018012

To the Editor.  —I read with interest the article by Morris and Estes.1I and other gastroenterologists have been using intravenous midazolam (versed) for sedation prior to endoscopy and have found that amnesia during the procedure and for a short time afterward is a common finding, even when the patient remains somewhat awake during the time. In my experience, I have had a patient ask a question and receive an answer at the completion of the examination only to ask the same question several times during the next hour without recalling these repetitions.This particular aspect of the action of intravenous midazolam therapy is particularly useful with endoscopy in that patients who require repeated examinations do not recall the discomfort of the previous ones, allowing a lighter level of sedation than might otherwise be necessary.