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April 27, 1994

Immunity to Measles Among Health Care Workers in France

Author Affiliations

Hospital of Orleans Orleans, France

JAMA. 1994;271(16):1239. doi:10.1001/jama.1994.03510400025021

To the Editor.  —The Centers for Disease Control and Prevention editorial note1 raises an important question concerning measles susceptibility in adults. It is pointed out that a reduction in measles susceptibility may have occurred through increased measles vaccination among preschool-aged children. Nevertheless, measles screening for health care workers in the United States revealed significant numbers of nonimmune hospital employees.2,3 We studied measles immunity in hospital employees in Orleans, France, a country where vaccination coverage is much lower than that reported in the United States.During the first few months of 1993, 465 serum samples were tested by enzyme immunoassay for measles antibody (IgG). This represented 14% of the employees. Of these 465 employees, four were seronegative. Of those born before 1957, none (0%) tested seronegative, while four (2%) of those born in or after 1957 were seronegative.The number of nonimmune hospital employees was lower in France than

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