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July 11, 1980

Avoidance of Surgical Hyperglycemia in Diabetic Patients

Author Affiliations

From the Clinical Investigation Center, Naval Regional Medical Center, Oakland, Calif.

JAMA. 1980;244(2):166-168. doi:10.1001/jama.1980.03310020042026

Strict intraoperative glucose level control was accomplished with constant low-dose glucose infusion of 100 mg/kg/hr and variable infusion rates of insulin to control serum glucose levels as follows: 20 units/hr for serum glucose levels greater than 200 mg/dL, 1 unit/hr for levels between 80 and 200 mg/dL, and no insulin for levels less than 80 mg/dL. Using this technique, eight diabetic patients with serum glucose levels greater than 250 mg/dL before surgery had their serum glucose levels brought rapidly under control (ie, glucose level less than 200 mg/dL), which continued postoperatively.

(JAMA 244:166-168, 1980)