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August 22, 1980

Nitrous Oxide Analgesia-Reply

Author Affiliations

University of Texas Southwestern Medical School Dallas

JAMA. 1980;244(8):769. doi:10.1001/jama.1980.03310080011010

In Reply.—  Dr Hindin raises valid points that were considered by us in preparing our report. We are currently measuring the levels of N2O that accumulate in the mobile unit but do not have enough data at this time for an estimate of importance. The referenced article by Bruce and Bach1 allowed personnel to breathe trace gases for four hours at a time. The average time of transport in our series was 11 minutes. We do agree that every effort should be made to minimize the exposure to trace anesthetic gases.Few, if any, drugs that provide potent analgesia should be classified as benign. This technique is one of the best, we think, for providing potent analgesia while minimizing side effects as it is self-administered and limited by requiring conscious effort on the part of the patient. Clinically, the effects on patients in pain, as opposed to tranquil