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April 16, 1982

Neurogenetic Directory

Author Affiliations

The Bowman Gray School of Medicine Wake Forest University Winston-Salem, NC


part 1, edited by Ntinos C. Myrianthopoulos (Handbook of Clinical Neurology, vol 42, P. J. Vinken and G. W. Bruyn, eds), 772 pp, with illus, $183, New York, Elsevier/ North-Holland Inc, 1981.

JAMA. 1982;247(15):2162. doi:10.1001/jama.1982.03320400072052

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Here is No. 42 of the epic work in which Vinken and Bruyn have undertaken to assemble the body of knowledge of clinical neurology. This potpourri volume contains much that has already been published elsewhere within the set but in fragmentary form.

In the preface is the surprising statement that about one third of all disorders known or suspected to be of genetic origin affect the nervous system. The editors add that most neurologists are unable to use genetic information for the management of their patients owing perhaps to the meager training most have had in this field. By collecting such information in one location, presumably isolated examples of neurogenetic disorders will be brought to the attention of the scientific community so that further cases can be added.

This broad subject is covered by limiting each consideration to a page or two of clinical pathological, biochemical, epidemiologic, and genetic characteristics