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Article
May 6, 1988

Small Intestinal Myeloid Metaplasia

Author Affiliations

From the Department of Internal Medicine A (Drs Schreibman and Alroy), and the Institutes of Hematology (Drs Brenner and Tatarsky), Gastroenterology (Dr Jacobs), and Pathology (Dr Ben-Arieh), Rambam Medical Center and Faculty of Medicine, Technion Institute of Medicine, Haifa, Israel.

From the Department of Internal Medicine A (Drs Schreibman and Alroy), and the Institutes of Hematology (Drs Brenner and Tatarsky), Gastroenterology (Dr Jacobs), and Pathology (Dr Ben-Arieh), Rambam Medical Center and Faculty of Medicine, Technion Institute of Medicine, Haifa, Israel.

JAMA. 1988;259(17):2580-2582. doi:10.1001/jama.1988.03720170056034
Abstract

Extramedullary hematopoiesis is rarely found in the gastrointestinal tract. A patient with postpolycythemic myeloid metaplasia who previously underwent splenectomy presented with recurrent, protracted gastrointestinal tract hemorrhage. Elaborate workup failed to reveal the source of bleeding. Intraoperative endoscopy with transillumination disclosed multiple submucosal lesions along the entire small bowel, which proved to be extramedullary hematopoiesis. After institution of hydroxyurea therapy, the rate of bleeding diminished considerably.

(JAMA 1988;259:2580-2582)

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