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October 3, 1980

Chemical Diagnosis of Disease

Author Affiliations

Emory University School of Medicine Atlanta


edited by Stanley S. Brown, Frederick L. Mitchell, and Donald S. Young, 1,383 pp, with illus, $74.75, New York, Elsevier/North Holland Inc, 1979.

JAMA. 1980;244(14):1622. doi:10.1001/jama.1980.03310140080044

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This encyclopedic volume is a collection of minimonographs on the biochemistry of disease and the use of chemical tests in medical diagnosis. The editors are well known for their contributions to clinical chemistry and chemical pathology. The 38 contributors are a distinguished group of physicians and laboratory scientists, most of whom are from Great Britain. The objective of this monumental editorial effort was to provide a comprehensive source of information on the interpretation of laboratory tests in clinical chemistry.

Diagnostic tests can be discussed from any one of several perspectives: the method of analysis, the entity measured, the organ or organ system involved, or the disease process being considered. Integration of information derived from these different perspectives and formulation of a logical presentation is not a simple task. The editors have purposely omitted discussion of methodology except where it is essential to interpretation of results, and chapters are organized either