November 7, 1980

Torulopsis glabrata Endocarditis

Author Affiliations

From the Division of Infectious Diseases, St Thomas Hospital, and the Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn.

JAMA. 1980;244(18):2088-2089. doi:10.1001/jama.1980.03310180054037

TORULOPSIS glabrata is a fungal organism of the family Cryptococcaceae with low pathogenicity for man. It is a frequent saprophyte and can be cultured from the stool, skin, mouth, and vagina in healthy persons. Infections due to T glabrata occur principally in patients whose immune systems are suppressed, have indwelling venous or urinary catheters, or have been treated with broad-spectrum antibiotics.1 Documented cases of endocarditis due to T glabrata are uncommon; predisposing causes and clinical features have not been reviewed.

A patient had tricuspid valve endocarditis secondary to T glabrata. Her illness followed abdominal surgery and was characterized by 33 months of episodic chills and fever. Other patients with T glabrata endocarditis have been described with features remarkably similar to those of our patient.2,3 These similarities prompted this case report and review of the literature.

Report of a Case  A 63-year-old diabetic woman had undergone a uretero-ureterostomy for