May 14, 1982

Treatment of Group A Streptococcal Pharyngotonsillitis-Reply

Author Affiliations

University of Minnesota School of Medicine Minneapolis

JAMA. 1982;247(18):2496. doi:10.1001/jama.1982.03320430020008

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


In Reply.—  The possible role of β-lactamase-producing bacteria in protecting group A streptococci from the activity of penicillin is not precisely clear. As Dr Brook indicates in his letter, the reasons for high failure rates in second and third courses of penicillin are "still unknown and speculative." I believe further confirmation of the cited studies is necessary to place all of the issues in perspective.