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June 24, 1988

Trial Appears to Confirm Safety of Chorionic Villus Sampling Procedure

JAMA. 1988;259(24):3521-3522. doi:10.1001/jama.1988.03720240001001

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CHORIONIC VILLUS SAMPLING (CVS) is just about as safe for mother and fetus as amniocentesis, according to the newly announced initial results of an ongoing study conducted by the National Institute of Child Health and Human Development (NICHD), Bethesda, Md. George G. Rhoads, MD, chief of the institute's Epidemiology Branch and director of the study, discussed the risks assessed and knowledge gained at the annual meeting of the American College of Obstetricians and Gynecologists in Boston.

In the NICHD Chorionic Villus Sampling Collaborative Trial, which began in 1984, investigators have utilized a new pump-type sampler to aspirate a specimen of placental tissue by the transcervical method. In the remaining years of the six-year study, research will focus on the performance and safety of transabdominal CVS, in which a needle is put through the abdomen to extract a small amount of placental tissue. Laird G. Jackson, MD, director, Division of Medical