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We would agree with Dr Clark that anecdotal reports and collective reviews gathered from the medical literature attesting to an association between hyperparathyroidism and pancreatitis cannot be construed as providing sound evidence of a cause-and-effect relationship. Certainly, pancreatitis can develop in the presence of hypercalcemia, but this appears to be a rare phenomenon, and no satisfactory explanation for a possible causal mechanism has yet been proposed. Our principal purpose in publishing this experience was not to tilt at shibboleths but simply to remind physicians that pancreatitis in the presence of hypercalcemia may have another cause.
Edis AJ, Bess MA, van Heerden JA. Hyperparathyroidism and Pancreatitis-Reply. JAMA. 1980;244(21):2413. doi:10.1001/jama.1980.03310210015007