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Article
July 8, 1988

Several Research Avenues May Improve Understanding of Multiple Sclerosis

JAMA. 1988;260(2):155-159. doi:10.1001/jama.1988.03410020015004

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Abstract

RESTLESS LEGS and lagging libidos are two problems associated with multiple sclerosis for which potential solutions were offered at the 40th annual meeting of the American Academy of Neurology in Cincinnati. Also newly reported is the value of magnetic resonance imaging in studying the progress of this disease.

Frederick M. Vincent, MD, clinical associate professor of medicine and psychiatry at Michigan State University College of Human Medicine, East Lansing, presented preliminary data from a small group of patients that, he said, "appear quite promising" for helping to combat the chronic fatigue known to more than 90% of persons with multiple sclerosis.

Vincent, who recently served as chief of neurology in the university's Department of Medicine, was treating a patient who did not respond well to amantadine hydrochloride (Symmetrel), the standard drug therapy for multiple sclerosis—associated fatigue. The patient, as it happened, was among the estimated 5% or so of the

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