Two therapeutic regimens were used to treat vulvovaginal candidiasis with clotrimazole vaginal tablets. The purpose of this study was to compare the efficacy of a three-day double-dose schedule with that of a seven-day single-dose schedule. Both regimens were comparable in eliminating the Candida sp.
Robertson WH. A Concentrated Therapeutic Regimen for Vulvovaginal Candidiasis. JAMA. 1980;244(22):2549-2550. doi:10.1001/jama.1980.03310220047027