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December 5, 1980

Clinical Immunology

Author Affiliations

Case Western Reserve University Cleveland


2 vol, edited by Charles W. Parker, 1,438+ pp, 293 illus, $80 ($40/vol), Philadelphia, WB Saunders Co, 1980.

JAMA. 1980;244(22):2566. doi:10.1001/jama.1980.03310220064043

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Parker's Clinical Immunology is the latest to swell the ranks of books in this growing field. However, it should appeal to a large audience, particularly to the nonimmunologist clinician.

This two-volume, 1,438-page opus is the product of some 60 authors. It probably should not be viewed as an immunology book (at the risk of scaring off some of its intended audience), but as a text of clinical medicine that concentrates on diseases in which immunologic mechanisms are important. To facilitate understanding of the subject for the nonimmunologist reader, the first 400 pages are devoted to basic immunology. Topics such as lymphocyte biology, autoimmunity, complement, immune complexes, and inflammation are discussed with outstanding clarity, aided by explanatory diagrams and tables. I found these sections reasonably up to date and relevant to human disease. A topic I particularly enjoyed for its concise and lucid presentation was lymphocyte subpopulations (helpers-suppressors). References to the