January 2, 1981

Infections in the Abnormal Host

Author Affiliations

Pittsfield, Mass


edited by Michael H. Grieco, 1,035 pp, with illus, $65, New York, Yorke Medical Books, 1980.

JAMA. 1981;245(1):77. doi:10.1001/jama.1981.03310260055036

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This work is divided into three major sections. Part 1 discusses abnormalities in host defenses, including congenital and acquired defects, and a chapter on the effects of malnutrition. Care of the long-term hospitalized patient is emphasized in this chapter. Although current, the section points out the great need for further research into the specific defects of the immune system of the host.

Part 2, the heart of the book, concerns infections in specific abnormal hosts, including patients with endovascular and prosthetic implant infections and a unique chapter on intraocular infections. This chapter is deficient in information on intraocular bacterial infections—especially regarding the use of intraocular antibiotic therapy in this difficult clinical problem. The chapter on histopathologic responses to infection is excellent, with very instructive color plates.

Part 3, on the management of infections in the abnormal host, concludes the book. Antimicrobial therapy, chemotherapy for viral and chlamydial infections, and chemotherapy