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Article
September 16, 1988

Risk Factors for Ectopic Pregnancy-Reply

Author Affiliations

Centers for Disease Control Atlanta
University of Texas Houston
Methodist Center for Reproduction and Transplantation Immunology Indianapolis
Park Nicollet Medical Center St Louis Park, Minn
Mayo Clinic Rochester, Minn

Centers for Disease Control Atlanta
University of Texas Houston
Methodist Center for Reproduction and Transplantation Immunology Indianapolis
Park Nicollet Medical Center St Louis Park, Minn
Mayo Clinic Rochester, Minn

JAMA. 1988;260(11):1554. doi:10.1001/jama.1988.03410110061020
Abstract

In Reply.—  The comments by Drs Weiss and Daling give us an opportunity to elaborate on the interpretation of our study findings. There are two distinct research issues concerning the association between ectopic pregnancy and current IUD use: (1) the relative risk of ectopic implantation given that conception has occurred and (2) the relative risk of conception followed by ectopic implantation. The second relative risk is intrinsically tied to the relative risk of conception itself, while the first relative risk is not. Different control groups are required to assess these separate but related associations. We agree with Drs Weiss and Daling that a nonpregnant control group is required to evaluate the relative risk of conception followed by ectopic implantation. However, our study was not designed to assess this issue. Rather, our study was designed to assess the relative risk of ectopic implantation given that conception has occurred. To evaluate the

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