To the Editor.—
In reference to the article entitled "Cutting Into Cholesterol: Cost-Effective Alternatives for Treating Hypercholesterolemia" in the April 15 issue,1 it seems to me that the authors are comparing apples and oranges in their comparison of anion-exchange resins with oat bran. None of the cholesterol-lowering agents have been compared with each other in terms of efficacy and, except for the anion-exchange resin agents and gemfibrozil, I have not seen proof of decreased morbidity or mortality.
Evans JR. Cutting Into Cholesterol. JAMA. 1988;260(12):1718. doi:10.1001/jama.1988.03410120063026