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July 6, 1994

In the Name of Science: Issues in Responsible Animal Experimentation

Author Affiliations

University of California, Los Angeles Center for the Health Sciences

JAMA. 1994;272(1):75-76. doi:10.1001/jama.1994.03520010093043

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The title tells a good part of the story: In the Name of Science: Issues in Responsible Animal Experimentation is about attitudes, ethical arguments, legislation, protocol review, animal pain scales, and so forth, all issues that are on center stage in the debate over animal experimentation.

For readers not familiar with the factions, they are somewhat as follows. Two extreme points of view bracket the debate. The proponents of one argue that literally any type of research using animal subjects is defensible—indeed, even desirable—provided the outcome of the research is likely to provide some valuable information about humans, eg, human behavior, human disease, disease cure. The proponents of the other argue essentially the opposite, namely, that any use of animals as experimental subjects is unacceptable no matter what the supposed benefits to humankind. At times members of the latter group will engage in criminal activities. Between these two extremes is

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