[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.147.238.168. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
April 7, 1989

Pathogenesis and Immunity in Pertussis

Author Affiliations

Lloyd Noland Hospital and Health Centers Fairfield, Ala

Lloyd Noland Hospital and Health Centers Fairfield, Ala

 

edited by Alastair C. Wardlow and Roger Parton, 482 pp, with illus, $124, New York, NY, John Wiley & Sons, 1988.

JAMA. 1989;261(13):1981-1982. doi:10.1001/jama.1989.03420130151042

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

This is a 482-page authoritative text with 31 contributors who are among the most active investigators in the field of pertussis from six countries including the United Kingdom (16), Canada (2), France (2), Norway (1), Japan (5), and the United States (5). In 21 chapters the authors comprehensively present relevant new information concerning all aspects of pertussis. Each chapter begins with a brief introduction for the nonspecialist and concludes with a bibliography that contains the most recently published literature and often key historical references. There is an excellent blending of scientific information with practical clinical and vaccine applications.

The first half of the book reviews the microbiology of Bordetella pertussis, including growth characteristics of the microorganism and its products. The combined technologies of transposon mutagenesis and recombinant DNA technology have catapulted our understanding of both the pathogenesis of pertussis and the molecular organization of the genes determining virulence. Most of

×