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Article
June 2, 1989

Unique Aspects of Heart and Lung Transplantation Exhibited in the 'Domino-Donor' Operation

Author Affiliations

From the Department of Surgery, Division of Cardiac Surgery (Drs Baumgartner, Cameron, Fonger, and Reitz and Mr Birenbaum), and the Department of Medicine, Division of Cardiology (Dr Traill), The Johns Hopkins Medical Institutions, Baltimore, Md.

From the Department of Surgery, Division of Cardiac Surgery (Drs Baumgartner, Cameron, Fonger, and Reitz and Mr Birenbaum), and the Department of Medicine, Division of Cardiology (Dr Traill), The Johns Hopkins Medical Institutions, Baltimore, Md.

JAMA. 1989;261(21):3121-3125. doi:10.1001/jama.1989.03420210069018
Abstract

During the past 2 decades various refinements in heart and lung transplantation procedures have taken place. Improved preservation methods, new immunosuppressive medications, and advances in technical capabilities have allowed innovative procedures to be performed. In May 1987 the first "domino-donor" operation was performed in the United States. A 28-year-old man with cystic fibrosis and end-stage lung disease received the heart and lungs of an anonymous donor after he donated his heart to a 38-year-old man with end-stage ischemic cardiomyopathy. The technical and logistical aspects of this transplantation procedure are described herein. Other unusual features of this case that are discussed include heart-lung transplantation for a patient with cystic fibrosis, the use of cardiopulmonary bypass to allow lung procurement and transplantation across long distances, and the current role of heterotopic cardiac transplantation.

(JAMA. 1989;261:3121-3125)

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