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September 14, 1994

Sclerodermalike Esophageal Disease in Children of Mothers With Silicone Breast Implants

Author Affiliations

San Francisco, Calif

JAMA. 1994;272(10):768-769. doi:10.1001/jama.1994.03520100031023

To the Editor.  —Analysis of the data presented by Drs Levine and Ilowite1 raises several questions. Of the 26 children who were born of mothers with silicone breast implants and who presented with abdominal pain and additional symptoms, only 11 children from six families were evaluated. Fifteen of these 26 individuals, although purportedly presenting for concerns about second-generation effects, "refused the study." No comment was made nor was any follow-up available on these 15 children and whether their abdominal complaints progressed. Why would more than half of the patients initially complaining of abdominal pain and associated symptoms then deny thorough evaluation? Furthermore, as one reviews the data, the eight individuals who agreed to proceed with the study came from only four families. It is reported that six individuals had "significant abnormal esophageal motility." We are not, however, informed as to how many families are involved. From the presented data,

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