November 17, 1989

Multiple Sclerosis and Human Interferon Alfa-Reply

Author Affiliations

Hôpital Beaujon Clichy, France

Hôpital Beaujon Clichy, France

JAMA. 1989;262(19):2684. doi:10.1001/jama.1989.03430190064029

In Reply.—  We certainly agree with Dr Coyle that hyperthermia caused by interferon1 is one of the possible mechanisms by which interferon may have induced exacerbation of multiple sclerosis in our patient.