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January 5, 1990

Stuttering and Acquired Immunodeficiency Syndrome

Author Affiliations

University of Massachusetts Medical Center Worcester

University of Massachusetts Medical Center Worcester

JAMA. 1990;263(1):38. doi:10.1001/jama.1990.03440010036022

To the Editor.—  I report a case of stuttering in a patient infected with the human immunodeficiency virus. The stuttering subsequently resolved with treatment with zidovudine.

Report of a Case.—  A 27-year-old Hispanic man positive for human immunodeficiency virus antibody presented with complaints of weight loss, fever, fatigue, diarrhea, difficulty with memory, and "haziness of mind." The results of the examination were remarkable for a temperature of 37.7°C, cervical and inguinal lymphadenopathy, and an inability to recall four objects after 3 minutes. Remarkable laboratory results were a T4-lymphocyte count of 240, a cytomegalovirus titer of 3.74 enzyme-linked immunosorbent assay units, and a negative rapid plasma reagin test. A lumbar puncture done 7 weeks later, because of continued memory loss and fever, produced cerebrospinal fluid with 2 red blood cells and 7 white blood cells per high-power field. Cultures of cerebrospinal fluid for fungi and bacteria were negative, as were