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Article
January 19, 1990

Psychoactive Drug Use and AIDS

Author Affiliations

San Bruno, Calif

San Bruno, Calif

JAMA. 1990;263(3):371. doi:10.1001/jama.1990.03440030054010
Abstract

To the Editor.—  In their study of drug abuse and acquired immunodeficiency syndrome in homosexual men, Kaslow et al1 stated that drug abuse was not associated with low mean T-helper cell counts at enrollment and that psychoactive drugs did not enhance the progression of human immunodeficiency virus infection. Their three categories of users included (1) use in last 2 years, but nonuse for 6 months; (2) use in last 6 months; and (3) use in last 7 days. Their data reveal that within the three categories and considering only marijuana, nitrites, and cocaine, 9.6% to 17.2% of seronegative subjects and 56.2% to 68.8% of seropositive subjects had CD4+ cell counts of less than 0.6×109/L. A greater number of seropositive subjects than seronegative subjects admitted to psychoactive drug use within the last 7 days: 1.6 times as many for marijuana, 1.5 times as many for nitrites, and

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