Fatal brain abscesses caused by Zygomycetes occurred in two patients known to be parenteral drug abusers. An immunodiffusion test for detection of antibodies to Zygomycetes demonstrated a band of identity in the serum of both patients. Prompt brain biopsy and culture, along with serological testing, may lead to a more rapid diagnosis and treatment of this fungal infection.
Pierce PF, Solomon SL, Kaufman L, Garagusi VF, Parker RH, Ajello L. Zygomycetes Brain Abscesses in Narcotic Addicts With Serological Diagnosis. JAMA. 1982;248(21):2881-2882. doi:10.1001/jama.1982.03330210063037