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March 16, 1990

Mapping Our Genes: Genome Projects: How Big, How Fast?

Author Affiliations

Case Western Reserve University Cleveland, Ohio

Case Western Reserve University Cleveland, Ohio

JAMA. 1990;263(11):1571-1572. doi:10.1001/jama.1990.03440110149045

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Few scientific projects have excited the imagination or generated the controversies that are associated with the effort to map the human genome. Comprehensive studies of a human genome project followed a proposal by Renato Dulbecco in 1986 to sequence the human genome completely in order to solve fundamental problems of cancer. One study was undertaken by the National Research Council of the National Academy of Science. The second was done by the Office of Technology Assessment (OTA) of the US Congress. The two reports were released in early 1988.

Mapping Our Genes: Genome Projects: How Big, How Fast? is the report issued by the OTA. The report was prepared by the OTA Human Genome Project staff with the assistance of an advisory panel comprised of leading scientists from industry and the academic community who represent a variety of disciplines and interests.

The report is well organized and well written. It