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November 2, 1994

Active Compression-Decompression CPR-Reply

Author Affiliations

University of Minnesota Minneapolis

JAMA. 1994;272(17):1326. doi:10.1001/jama.1994.03520170035023

In Reply.  —Dr Mazziotti points out some of the challenges in designing and executing a study to determine the effectiveness of different methods of CPR. When comparing two treatment groups, it is essential that both methods of CPR are performed correctly, in similar patient populations, and that the study design enables adequate data acquisition of critical variables associated with the research, as described by the Utstein conference on uniform standards for CPR research.1In our evaluation of the effectiveness of ACD CPR in patients with out-of-hospital cardiac arrest, our study was designed to maximize the clinical similarities between patients in both treatment groups. Data were collected according to the Utstein recommendations. Mazziotti points out the importance of similar clinical characteristics between groups. In our study, both the standard CPR group and the ACD CPR group had very similar baseline characteristics in terms of age, sex, prior cardiac history, presenting

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