July 4, 1990

Neurobiology of Disease

Author Affiliations

Harvard Medical School Beth Israel Hospital Boston, Mass

Harvard Medical School Beth Israel Hospital Boston, Mass


edited by Alan L. Pearlman and Robert C. Collins, 482 pp, with illus, $55, ISBN 0-19-505318-4, New York, NY, Oxford University Press Inc, 1990.

JAMA. 1990;264(1):94-95. doi:10.1001/jama.1990.03450010102041

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Starting approximately twenty years ago, neuroanatomy and neurophysiology appropriately were combined under the designation neurobiology. Unfortunately, at about the same time, neuropathology, as one of the basic sciences, began its steady downward trend so that at the present time, it is not usually included in neurobiology teaching. It may well be relevant to remember Derek Denny-Brown's remark, "The basic science of neurology is neuropathology."

This book addresses medical students and physicians as well as graduate students and scientists in neurobiology; from its contents, it is clear that it is not designed for the experienced clinical or basic neuroscientist. The first of its two parts deals with functional and anatomic systems, the second with disease processes.

As frequently occurs in multiauthored compendiums, there is great variability in style and quality. In most instances, however, the discussions are clear and the illustrations well chosen. An attractive feature consists of the presentation in