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February 1, 1995

Genes V

Author Affiliations

Baylor College of Medicine Houston, Tex

JAMA. 1995;273(5):424. doi:10.1001/jama.1995.03520290078037

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The fifth edition of this well-established classic textbook in molecular genetics is a "must read" for individuals, including medical students, residents, fellows, and attending physicians, interested in medical and human genetics. It will also be useful for practicing physicians with little knowledge of molecular genetics who wish to gain a better understanding of the excitement conveyed in the lay press regarding disease gene identification and the Human Genome Project, but who don't know where to start to obtain the necessary background.

It certainly has become apparent over the past several years that the tools of genetics and molecular biology are playing an ever-increasing role in understanding the mechanisms of disease processes. This is true not only for single-gene disorders that segregate in a Mendelian fashion, but also in diseases for which there are inherited susceptibilities, such as cancer and heart disease. In addition, molecular genetic methodologies are having direct impact

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