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April 26, 1995

Correcting the Code: Inventing the Genetic Cure for the Human Body

Author Affiliations

The Johns Hopkins Medical Institutions Baltimore, Md

JAMA. 1995;273(16):1304-1306. doi:10.1001/jama.1995.03520400074053

The title of Larry Thompson's book is as misleading as the headlines announcing new genetic discoveries: both promise more than the research portends. Correcting the Code is a fascinating account of the history of gene therapy going back to the classic experiment of Avery, McCarty, and MacCleod. With their demonstration that DNA from one strain of bacteria could transform the polysaccharide capsule of others, these scientists not only showed DNA to be the genetic material but became the first gene therapists.

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