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August 23, 1995

Acute Hepatitis and Renal Failure Following Ingestion of Raw Carp Gallbladders-Maryland and Pennsylvania, 1991 and 1994

JAMA. 1995;274(8):604. doi:10.1001/jama.1995.03530080020017

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MMWR. 1995;44:565-566

IN SOME cultures, eating gallbladders from certain species of snakes, birds, or fish is believed to improve health. A syndrome of acute hepatitis and renal failure following the ingestion of raw carp gallbladders has been described previously among persons living in Asia.1-4 This report summarizes two cases of this syndrome that occurred in residents of Pennsylvania who had eaten the raw bile and gallbladders of carp caught in Maryland.

Patient 1.  On July 11,1991, a 59-year-old man who had immigrated from Korea ate the uncooked gallbladder of a carp he had caught in Maryland from a tributary of the Susquehanna River. Six hours after eating the gallbladder, he developed diarrhea and abdominal pain. On July 14, he was admitted to a hospital with mild jaundice and persistent nausea and vomiting. Laboratory testing revealed elevated levels of serum creatinine (10 mg/dL [normal: 0.7-1.5 mg/dL]), total bilirubin (3.5 mg/dL

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