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August 23, 1995

Williams Hematology

Author Affiliations

University of Chicago Medical Center Chicago, Ill


edited by Ernest Beutler, Marshall A. Lichtman, Barry S. Coller, and Thomas J. Kipps, 5th ed, 1881 pp, with illus, $135, ISBN 0-07-070386-8, New York, NY, McGraw-Hill, 1995.

JAMA. 1995;274(8):661. doi:10.1001/jama.1995.03530080077053

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The fifth edition of Williams Hematology is a comprehensive textbook, which covers clinical aspects, basic science, and laboratory testing in this rapidly evolving field. A distinguished group of 95 experts has contributed the 210 chapters.

Introductory chapters discuss clinical assessment of patients, examination of blood and bone marrow, and hematology of the newborn and the aged. There follows an extensive review of subjects in molecular hematology, including aspects of molecular biology, cytogenetics, and immunology pertinent to an understanding of modern hematology. Considerable attention is given to such therapeutic areas as pharmacology of antineoplastic drugs, use of cytokines, marrow transplantation, pain management, and the potential role of gene therapy in hematology.

The classic hematologic disorders are then presented by system in concise monographs. There is expanded coverage of hemostasis and thrombosis and disorders of the immune system. A more comprehensive section on transfusion medicine topics is particularly useful. The traditional appendix

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