To the Editor.
—The report of the Dietary Intervention Study in Children (DISC)1 is an unimpressive account of the hypocholesterolemic effects of low-fat feeding to hypercholesterolemic children 8 to 10 years of age. Rather, it constitutes better support for the proposition that prepubertal boys and girls aged 8 to 10 years with low-density lipoprotein cholesterol (LDL-C) levels at or above the 80th percentile should be permitted to continue their ad libitum diets containing 34% of energy from fat, since after 3 years, the difference in plasma lipoproteins between the two groups was minuscule.The change in total cholesterol levels in the DISC special intervention group after 3 years was -0.43 mmol/L (-16.7 mg/dL) vs -0.35 mmol/L (-13.6 mg/dL) in the usual care group, a difference of 0.08 mmol/L (3.23 mg/dL). The changes in LDL-C were -0.40 mmol/L (-15.3 mg/dL) vs -0.31 mmol/L (-11.9 mg/dL), a difference of 0.09 mmol/L
Olson RE. Reducing Dietary Intake of Fat and Cholesterol in Children. JAMA. 1995;274(18):1423. doi:10.1001/jama.1995.03530180017009