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July 19, 1971

Nitroglycerin Tablets Loss of Potency

Author Affiliations

Carson, Calif

JAMA. 1971;217(3):340. doi:10.1001/jama.1971.03190030064018

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To the Editor.—  In reference to the communication on nitroglycerin (216:878, 1971), I believe the study was incomplete because it did not include the polyethylene container used to package nitroglycerin. The polyethylene container did pass Food and Drug Administration tests for packaging, and the product retains its potency for up to five years in an unopened container. The manufacturer has instructed the pharmacist on the container label to "dispense in glass or polyethylene only."Thus it would be correct to dispense nitroglycerin tablets in glass or polyethylene containers.