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December 13, 1995

Psychopharmacology: The Fourth Generation of Progress

Author Affiliations

University of California, San Diego School of Medicine La Jolla

JAMA. 1995;274(22):1813-1814. doi:10.1001/jama.1995.03530220079046

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The number 2002 has various connotations in our current thinking: the year of a balanced budget and Medicare bankruptcy. But in the realm of psychopharmacology, 2002 is the number of pages in the latest edition of this definitive book on the subject. At 11 lbs it is a behemoth, but the material therein is an argosy of medical information. It is a major advance over the very good previous edition, Psychopharmacology: The Third Generation of Progress, reviewed in JAMA (1988;259:1392).

The 317 contributors from around the world include the best and the brightest minds from the fields of academic and commercial psychopharmacology. Of the 163 chapters, approximately one third deal with the preclinical issues and the remainder with clinical disorders. Subject material extends far beyond the field of psychopharmacology. The use of imaging techniques is not only discussed separately, but also permeates the discussions of both research and clinical issues.

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