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November 20, 1991

Fundamental Virology

Author Affiliations

University of Rochester (NY) Medical Center

University of Rochester (NY) Medical Center


edited by Bernard N. Fields and David M. Knipe, 2nd ed, 1064 pp, with illus, $75, ISBN 0-88167-683-7, New York, NY, Raven Press, 1991.

JAMA. 1991;266(19):2760-2761. doi:10.1001/jama.1991.03470190108043

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This is a condensed version of the textbook Fields Virology, although "condensed" really overstates the fact. It is over 1000 pages packed with information sufficient to please most readers.

The second edition is a significant change from the first edition of Fundamental Virology, published in 1986. Eighteen former contributors are not in the second edition, but 24 new ones appear. As before, but in a more clear-cut manner, the text has two basic sections: chapters 1 through 15 address general topics such as virus taxonomy, analysis of viral membranes, defective viral genomes, and pathogenesis of a viral infection, whereas the second section treats individual viruses in great detail. Four chapters of the first edition have been removed from the introductory section, although some of that information has been included in the new edition under other chapters. However, some of the information, for example, antiviral chemotherapy and epidemiology of virus infection,