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November 27, 1991

Textbook of Medical Physiology

Author Affiliations

Indiana University School of Medicine Gary

Indiana University School of Medicine Gary

JAMA. 1991;266(20):2909. doi:10.1001/jama.1991.03470200123049

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The eighth edition of the Textbook of Medical Physiology by Arthur C. Guyton, MD, is similar to the seventh edition with few changes or rearrangements. It is shorter by 67 pages (6.6%). The former Unit II discussion of blood cells, immunity, and blood clotting has been moved to Unit VI, where it follows the description of cardiovascular, renal, and acid-base physiology. Chapters 11 and 12, which deal with normal and abnormal electrocardiograms, have been significantly improved. Unit IV, which describes the circulation of blood, has been rearranged and updated. The nervous system material has been rearranged and ends with chapter 61 describing cerebral flow, cerebrospinal fluid, and brain metabolism.

Dr Guyton continues to present physiological principles in molecular and physical terms and introduces a new feature—two print sizes. Large print describes fundamental physiological information that medical students need to know. Smaller print represents nonbasic physiological information such as anatomy, chemistry,