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September 14, 1984

Respiratory Cryptosporidiosis in the Acquired Immune Deficiency SyndromeUse of Modified Cold Kinyoun and Hemacolor Stains for Rapid Diagnoses

Author Affiliations

From the Departments of Pathology (Drs Ma and Gillooley) and Medicine (Dr Kaufman), St Vincent's Hospital and Medical Center of New York; and the Department of Pathology, Veterans Administration Medical Center, Philadelphia (Dr Villaneuva).

JAMA. 1984;252(10):1298-1301. doi:10.1001/jama.1984.03350100028024

We report three cases of primary intestinal cryptosporidiosis with bilateral interstitial pneumonia. The diagnoses were made using two rapid (one-minute) staining procedures, modified cold Kinyoun's solution and a Hemacolor set, on touch preparations of lung biopsy material, sputum, and stool. Intracellular cryptosporidia oocysts in alveolar macrophages suggest possible hematogenous spread of this agent. Opportunistic cryptosporidiosis should be included in the differential diagnosis of pneumonia in patients with acquired immune deficiency syndrome.

(JAMA 1984;252:1298-1301)