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January 4, 1985

Identification of Xanthochromia

Author Affiliations

University of Southern California School of Medicine Los Angeles

JAMA. 1985;253(1):39. doi:10.1001/jama.1985.03350250047009

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To the Editor.—  I have recently observed a particularly effective way to evaluate CSF visually for the presence of xanthochromia. The usual procedure consists of centrifugation of bloody CSF, followed by placing the container of fluid next to a white object (usually a lab coat) or holding it up to a light source. The supernatant is then inspected for xanthochromia, sometimes compared with water in a similar container. I have found that a more effective approach is holding the CSF container next to an x-ray view box. Thus, an easily accessible, brightened white background makes xanthochromia easier to spot. I have found this to be more effective than the traditional techniques for identifying faint xanthochromia.