As the title indicates, H. F. Pizer has enlisted the experiences of the physicians and patients at the Massachusetts General Hospital (MGH), a pioneering transplant hospital, to compile a true patient's guide. After a brief introductory chapter by Paul Russell, one of the original transplant immunologist-surgeons, the history of transplantation is both eloquently and succinctly presented. Throughout, the authors, all prestigious members of the team, remain unidentified.
The problems faced by the patient dying of end-stage organ failure, some of the solutions already found by the transplant community, and unsolved problems are addressed in successive chapters. The well-established United Network for Organ Sharing (UNOS) is discussed in detail, including the critical shortage of organ donors as the primary limiting factor in achieving a successful transplantation for those many who do not live long enough to receive "the gift of life."
Subsequent chapters deal with the immune barrier, the second limiting
McCabe R, Leggett PH. Organ Transplants: A Patient's Guide. JAMA. 1992;267(20):2817. doi:10.1001/jama.1992.03480200125037