This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
A NEW variant of the subtype H3N2 of influenza virus A has emerged in the past 5 months. It is sufficiently different from the current subtype that it, or one antigenically similar, will be used in next year's influenza vaccine.
The new variant, called A/Wuhan/359/ 95, was isolated in Wuhan, China, in September. Since then it has turned up in several places in China, and in Singapore and Guam. Three isolates similar to it have been found in the United States.
Although two new variants of the other A virus subtype have also emerged during the past few months, they are not antigenically significantly different from the current vaccine, so the current strain, A/Texas/36/91, is being retained. Similarly, no new variant of influenza B virus has appeared, so the strain in the current vaccine, B/Harbin/7/94, is also being retained.
FDA and WHO Decide
The decision to switch to the new
Marwick C. Antigenically Different Subtype in New Flu Vaccine. JAMA. 1996;275(11):825. doi:10.1001/jama.1996.03530350007002