[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
July 15, 1992

Geriatric Medicine

Author Affiliations

Travelers Center on Aging, University of Connecticut Health Center, Farmington

JAMA. 1992;268(3):360-362. doi:10.1001/jama.1992.03490030072033

Stroke is a major cause of morbidity and mortality in older men and women, and advanced age is the most consistent risk factor for all types of stroke.1 Recent controlled studies evaluating the treatment of two major risk factors for stroke, isolated systolic hypertension (ISH) and nonvalvular atrial fibrillation, have shown considerable benefit in reducing stroke rate, even in the oldest age groups.

Defined as systolic blood pressure greater than 160 mm Hg and diastolic blood pressure less than 90 mm Hg, ISH increases with age secondary to a decrease in arterial compliance.2 The risks of cardiovascular and cerebrovascular events are increased with ISH; for any given systolic blood pressure, the oldest age groups have the highest number of events.3,4

The Systolic Hypertension in the Elderly Program was initiated to examine the effectiveness of ISH treatment in persons older than 60 years.5 Just less than 5000