THE INCIDENCE of melanoma of the skin appears to be rapidly rising. The increased incidence may be partially attributable to increased detection resulting from screening. In 1992, approximately 32000 newly diagnosed cases and 6700 deaths are expected in the United States. Melanoma tends to occur in adults in the prime of their family and professional lives. Detection and surgical treatment of the early stages of this malignancy are usually curative. In contrast, diagnosis and treatment in late stages often have dismal results.
Traits associated with an increased risk of developing melanoma include multiple typical moles, atypical moles, freckling, history of severe sunburn, ease of burning, inability to tan, and light hair with blue eyes. Other factors include the presence of familial atypical mole and melanoma syndrome, disorders of DNA repair, and excessive sun exposure.
Efforts to increase public awareness of melanoma and its treatment without causing unnecessary fear present a
Goldsmith LA, Askin FB, Chang AE, Cohen C, Dutcher JP, Gilgor RS, Green S, Harris EL, Havas S, Robinson JK, Swanson NA, Tempero MA, Ackerman AB, Balch CM, Cascinelli N, Clark WH, Farmer ER, Guerry D, Houghton AN, Koh HK, Kopf AW, Kraemer KH, MacKie RM, Maize JC, Meyskens FL, Perednia DA, Piepkorn MW, Rigel DS, Rogers GS, Sagebiel RW, Sober AJ, Tucker MA, Wick MR, Zone JJ, Moshell AN, Blume E, Bray E, Elliott JM, Ferguson JH, Gregg MB, Hall WH, Henson DE, Katz SI, Lotze MT, Maize J, Safavi KH, Sober A. Diagnosis and Treatment of Early MelanomaNIH Consensus Development Panel on Early Melanoma. JAMA. 1992;268(10):1314-1319. doi:10.1001/jama.1992.03490100112037