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Article
August 23, 1985

Randomized Clinical Trials

Author Affiliations

Marshfield Medical Foundation Marshfield, Wis

JAMA. 1985;254(8):1032-1033. doi:10.1001/jama.1985.03360080042011
Abstract

To the Editor.—  I read with considerable interest the editorial by Dr Peter P. Morgan1 entitled "Randomized Clinical Trials Need to be More Clinical." I was somewhat amazed with the author's comment that a "randomized clinical trial requires clinicians to set aside their own judgments, asks patients to accept treatment that may be substandard,..." I have been a clinical investigator in several randomized trials. If I had believed I was asking a patient to accept substandard treatment, or had already made a judgment that I had "set aside" regarding any treatment modality, I would have felt obliged not to participate in that clinical trial.It is unethical, immoral, and unconscionable to encourage patients to accept any treatment a physician thinks is substandard.

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