November 1, 1985

Cholesterosis—Membrane Cholesterol: Theoretical and Clinical Aspects

Author Affiliations

Cook County Hospital Chicago


by Yu. M. Lopukhin et al (V. E. Tatarchenko, trans, Soviet Scientific Reviews Suppl Series Physicochemical Biology, vol 4, V. P. Skulachev, ed), 382 pp, with illus, $174, New York, NY 10276 (PO Box 786, Cooper Station), Harwood Academic Publishers, 1984.

JAMA. 1985;254(17):2477-2478. doi:10.1001/jama.1985.03360170117046

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One of the less well-known areas of US-Soviet competition has been over who had first claims to discoveries in atherosclerosis. It now seems settled that the Russians first recognized the role of dietary fat in producing hypercholesterolemia and atherosclerosis, and offered the first description of angina as a sign of the disease—all this around 1910. It was again the Russians, who, in the early 1920s, demonstrated higher levels of serum cholesterol in survivors of myocardial infarction. These contributions include most of the essential pieces of information about this disease that were accumulated in the first third of this century.

But where have the Soviets been since then? This book provides impressive evidence that contemporary research in atherosclerosis is again proceeding on a high level in the Soviet Union, at least within the confines of the Second Medical Institute in Moscow.

As with all such monographs, only a reader with an