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November 22, 1985

Is Remote Disease Associated With Candida Infection a Tomato?

Author Affiliations

State University of New York at Stony Brook

JAMA. 1985;254(20):2891. doi:10.1001/jama.1985.03360200041012

To the Editor.—  The correspondence between Crook,1 Edwards2 and Coleman3 recalled to me an almost forgotten history. The idea that intestinal putrefaction is a source of human ills can be traced to the ancients; I note only the connotations of "choleric" temperament and of "black bile." In the French court the clyster was in great demand. Purging was long a treatment for whatever came along, and laxatives are still found in nearly every household in the Western world. In the early years of this century, Abderhalden devised tests designed to identify and to measure degrees of autointoxication. In the second decade Cotton was famous for removing intestines of patients with "dementia praecox." Between 1930 and 1960 a large number of studies, especially by Baruk4 and his school, purported to relate psychoses to neurotoxins produced by more or less specific strains of Escherichia coli. An annotated bibliography is